Octacalcium Phosphates for use in toothpaste, teeth powder dentifrice

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It seems as though nano molecules of hydroxyapatite (HA), basically soluble HA, is what remineralizes teeth or bone best.  One way to achieve this is to mix soluble precursors to HA, and when exposed to water, these precursors combine to make nano hydroxyapatite.  In that case Tetracalcium phosphate and dicalcium phosphate can be used.  Peroxides also seem to help the soluble HA stick to surfaces.

Ca8 (HPO4)2 (PO4) 4

However another way to make nano hydroxyapatite is to hydrolyze a larger precursor to HA.  This could be Octacalcium Phosphate or another precursor to HA.

Octacalcium phophate will slowly hydrolyze or dissolve in water and release HA.  This is an execptional source for the natural remineralization of teeth or any other use at any concentration.





how to make:

easiest way to make probably 2 moles Dicalcium phosphate (DCP) and 2 moles Tricalcium phosphate (TCP) mixed in water at 37c for 3 hours.

2 moles Ca3(PO4)2  (MW: 310.18)
2 moles CaHPO4 2H20 (MW:172.09)
Ca8 (HPO4)2 (PO4) 4


62.04g Tricalcium Phosphate Annhydrous

34.42g Dicalcium Phosphate Dihydrate

Melt with HHO torch into Octacalcium Phosphate

cement method

water method

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