7.03.2019

Cox-2 natural inhibitor CBD vape recipe essential oils

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This is an open source invention laying out an anti-inflammatory vape mixture for use in vaping devices that is all-natural and organic.  COX-2 inhibition can help with chronic pain, insomnia, inflammatory conditions, and iron overload.

Basically, this invention is the addition of COX-2 (and/or cox-1 but preferably cox-2 specific) inhibiting plants or plant extracts into MCT oil or any other lipid and/or emulsifiers such as PEG/vegetable glycerine but most preferably caprylic acid.  Other inflammatory enzymes or markers may also be effected and/or target such as Nitrite, TNF-alpha, IL-10, IL-1beta, iNOS, etc.

Absorption enhancers like limonene or other terpenes or extracts can be also used.

Anti-microbial extracts can also be used to enhance health

If the person is low on cox-2 they can use plants that induce it like THC.

Some examples of oil soluble cox-2 inhibitors are CBD, Carvacrol, humulene, etc.

One example of a non-COX mediated anti-inflammatory is salvinorin or Salvia Divinorum.

<<<<DANGER! Many of the essential oils listed below are acetylcholine esterase inhibitors and may cause heart failure in vulnerable people.  Do not attempt any recipie of vaporized essential oils without doing all necessary research.  Pure limonene seems safe but most other essential oils with mixed terpenes are not.  See end of this post for my research on essential oils so far.>>>>>

Above only applies to burning the oil.  Vaping should be ok, although do stay away from oils high in ACHEI's.



Example recipie:

Dissolve 1g of high CBD kief (like that from blacktiecbd.net) into enough caprylic acid  to dissolve with gentle heating.  Since kief and other CBD hemp flower contain some THC, if a stronger liquid is desired then CBD isolate can be added (like from blacktiecbd.net).

Next terpenes and/or essential oils like oregano oil, orange oil, humulene, beta carophyllene, or hop oil, and lemongrass can be added to enhance the cox-2 effect and also to enhance absorption.

Humulene- cox-2 inhibitor
CBD- cox-2 inhibitor
Carvacrol- cox-2 inhibitor
Lemongrass- kills h pylori and absorption enhancer
Orange- absorption enhancer from limonene
Carrot- kills h pylori
Ginger- kills campylobacter
Eucalyptus- kills proteus, mycoplasma, corynebacteria (must use only a couple drops per ml max)
Peppermint- kills anaerobics
Cinnamon- kills pseudomonas and haemophilis
Juniper berry- kills tetanus

Example mixture:

24% essential oils and terpenes

4% orange
5% humulene
5% oregano
2% lemongrass
2% carrot
2% fresh ginger
1% eucalyptus
1% peppermint
1% cinnamon
1% juniper berry

60% kief and CBD

50% kief
10% CBD isolate

16% caprylic acid

Add this using a 1ml syringe into an empty 510 compatible vape cartridge if desired.

Iron induces (increases) cox-2
https://www.ahajournals.org/doi/full/10.1161/01.cir.103.19.2395

salvinorin-a anti-inflammatory
https://pubchem.ncbi.nlm.nih.gov/compound/Salvinorin-A#section=Therapeutic-Uses

<<<<ACHEI research>>>>


Careful of achei! Carophyllene delta-3-carene alpha pinene, camphor, 1,8 cineole
http://info.achs.edu/blog/aromatherapy-essential-oils-and-memory

Alpha pinene>camphor>1,8 cineole (achei potency)

Carophyllene- cloves, rosemary, cannabis, hops

3-carene- turpentine

Alpha pinene- Eucalyptus, orange, rosemary, pine, sage

Camphor- rosemary, coriander, sage

1,8 cineole- eucalyptus, camphor laurel, bay leaves, tea tree, sweet basil, wormwood, rosemary, sage, Cannabis sativa

Coriander composition linalool? Camphor, a-pinene
https://www.ijser.org/researchpaper/Effect-of-the-Environment-on-Content-and-Composition-of-Essential-oil-in-Coriander.pdf

Clove composition eugenol carophyllene
https://bioresources.cnr.ncsu.edu/BioRes_02/BioRes_02_2_265_269_Alma_ENK_CloveOil_Turkish.pdf

SO orange lemongrass oregano compositions

Orange has a little a-pinene like 1%

Lemongrass has a little camphor like 2%
https://www.researchgate.net/publication/271228112_Chemical_composition_and_citral_content_in_lemongrass_Cymbopogon_citratus_essential_oil_at_three_maturity_stages/download

Oregano has thujene, camphor, a pinene, carophyllene
https://www.researchgate.net/publication/254247452_Composition_of_Oregano_Essential_Oil_Origanum_vulgare_as_Affected_by_the_Use_of_Winery-Distillery_Composts/link/0deec5290f7f557e21000000/download

So need isolated carvacrol and limonene and h pylori oil

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